PHARMACEUTICAL FORMULATION COMPRISING ONE OR MORE FUMARIC ACID ESTERS IN AN EROSION MATRIX

EPO Patent Application EP 3295/936 A1
Application Date: Mar. 21st, 2018

ABSTRACT

A pharmaceutical formulation comprising an erosion matrix comprising one or more fumaric acid esters as well as one or more rate-controlling agents, wherein erosion of said erosion matrix permits controlled...
Assignee(s):
Inventor(s):
NILSSON, Henrik
RUPP, Roland
Application Number:
17170304.4
International Classification:
A61K 9/28 (20060101); A61K 31/215 (20060101); A61P 17/06 (20060101); A61K 9/20 (20060101); A61K 31/225 (20060101)
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CLAIMS

What is claimed is:

A pharmaceutical formulation in the form of an erosion matrix tablet comprising: i) 30-60 % by weight of one or more fumaric acid esters selected from di-(C1-C5)alkylesters of fumaric acid and mono-(C1-C5)alkylesters of fumaric acid, or a pharmaceutically acceptable salt thereof, as an active substance;ii) 3-6 % by weight of a...

DESCRIPTION

FIELD OF THE INVENTION

The present invention relates to a pharmaceutical formulation comprising an erosion matrix. More particularly the invention relates to a pharmaceutical formulation comprising an erodible matrix comprising one or more fumaric acid esters as well as one or more rate-controlling agents, wherein erosion of said erosion matrix permits controlled or sustained...
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