DEVELOPMENT OF CURCUMIN AND PIPERINE LOADED DOUBLE-LAYERED BIOPOLYMER BASED NANO DELIVERY SYSTEMS BY USING ELECTROSPRAY / COATING METHOD

USPTO Patent Application US 2018/0028447 A1
Application Date: Feb. 1st, 2018

ABSTRACT

A double-layered particle having a core layer formed of zein protein, in which the active agent curcumin and/or its derivatives are encapsulated, and an outer shell layer formed of chitosan...
Application Number:
15/554,658
International Classification:
A61K 9/16 (20060101); A61K 31/4525 (20060101); A23P 20/20 (20060101); A61K 9/51 (20060101); A61K 9/00 (20060101); A23L 33/105 (20060101); A61K 31/12 (20060101); A61K 9/50 (20060101)
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CLAIMS

What is claimed is:

1. A double-layered particle comprising: a. a core layer formed of zein protein, in which the active agent curcumin and/or its derivatives are encapsulated, andb. an outer shell layer formed of chitosan and/or its derivatives, in which the active agent piperine is encapsulated, and which is coated over said core layer.

DESCRIPTION

THE RELATED ART

The invention relates to the preparation of multi-layered nano/micro particles with high added value comprising curcuma extract and piperine by using electrospray/coating method and to the application thereof to supplemental food nano-formulations.
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