LOW BURST POLY-(LACTIDE/GLYCOLIDE) AND METHODS TO PRODUCE POLYMERS

EPO Patent Application EP 3202/814 A1
Application Date: Aug. 9th, 2017

ABSTRACT

A PLG copolymer material, termed a PLG(p) copolymer material, adapted for use in a controlled release formulation for a bioactive material is provided, wherein the formulation exhibits a reduced "initial...
Assignee(s):
Inventor(s):
Dadey, Eric
Middleton, John
Norton, Richard L.
Application Number:
15185218.3
International Classification:
C08G 63/664 (20060101); C08G 63/90 (20060101); C08G 63/08 (20060101); A61K 9/00 (20060101); A61K 47/34 (20170101); A61K 38/12 (20060101); A61K 38/08 (20060101)
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CLAIMS

What is claimed is:

1. A biocompatible, biodegradable, non-hydrolyzed PLG low-burst copolymer material for a controlled release formulation having a weight average molecular weight of about 10 kilodaltons to about 50 kilodaltons and a polydispersity index of about 1.4-2.0 and from which a removed copolymer fraction characterized by a weight average molecular weight of...

DESCRIPTION

CROSS-REFERENCE TO RELATED APPLICATIONS

This application claims the priority of provisional application U.S. Ser. No. 60/901,435, filed Feb. 15, 2007, which is incorporated herein by reference in its entirety.
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