Compositions and Methods for Succinate Production

USPTO Patent Application US 2017/0107526 A1
Application Date: Apr. 20th, 2017

ABSTRACT

The present application provides genetically modified yeast cell comprising an active succinate fermentation pathway, as well as methods of using these cells to produce succinate.
Application Number:
15/386,506
International Classification:
C12N 15/81 (20060101); C12N 9/00 (20060101); C12N 15/52 (20060101); C12N 9/88 (20060101); C12N 9/02 (20060101); C12P 7/46 (20060101); C12N 9/04 (20060101)
No Pictures Available

CLAIMS

What is claimed is:

1. A genetically modified yeast cell from the Pichia fermentans/Issatchenkia orientalis clade having an active succinate fermentation pathway from phosphoenolpyruvate or pyruvate to succinate, wherein the active succinate fermentation pathway comprises the reactions: (a) pyruvate to oxaloacetate;(b) oxaloacetate to malate;(c) malate to fumarate; and(d) fumarate to succinate,wherein the cell comprises an...

DESCRIPTION

CROSS REFERENCE TO RELATED APPLICATIONS

This application is a continuation of U.S. application Ser. No. 13/981,517, filed Jul. 24, 2013, which is a section 371 national phase of International Application No. PCT/US2012/022612, filed 25 Jan. 2012, entitled “COMPOSITIONS AND METHODS FOR SUCCINATE PRODUCTION,” which claims the benefit of U.S. Application Ser. No. 61/436,185, filed 25...
Back to Top